June 2022 – Norwegian Research Council awards MNOK 11.3 for new ARIA project
The project builds on the use of our inhouse-developed assays for a new application in Alzheimer’s disease. The aim is to develop a novel biomarker system to detect and monitor servere adverse side effects of new immunotherapies for Alzheimer’s. These immunotherapies have demonstrated promising effect in clinical trials, and four new treatments have filed for FDA approval. Yet, these severe side effects, known as ARIA (Amyloid-Related Imaging Abnormalities, brain hemorrhaging) occur in up to 40% of patients on high doses are not addressed with current diagnostic tools.
May 2022 – New office and lab
After three years as a start-up in ShareLab ‘s shared facilities , we are moving to new offices at Parallell Oslo that include our own fully furnished lab. The move allows us to both concentrate on development work and prepare for the coming market phase. With this, we are one step closer to bringing our Alzheimer’s blood test to the market.
December 2021 – Norwegian Research Council awards MNOK 15 for new Parkinson’s project
Pre Diagnostic’s application “Parkinson’s Disease Early Detection” was selected by the Council and we will commence the development of a new blood test for Parkinson’s disease in 2022. The four year project builds on the experience acquired through the development of PreADx, and will leverage the same core technological principle.
April 2021 – “Pre Diagnostics featured in Medtech Insight’s Start-Up Spotlight “
Pre Diagnostic’s intracellular approach to neurodegenerative disease diagnosis is attracting attention.
March 2021 – Pre Diagnostics profiled in 360DX article
The results of Pre Diagnostics’ clinical study represent “a good start and this technique clearly has great potential,” Dag Aarsland, chair of old age psychiatry at Kings College London, said in an interview. A blood test that shows an AUC of .8, or above, is what clinicians operating in the field require and is seen as “very promising,” said Aarsland, a long-time clinician and researcher with an interest in Alzheimer’s disease and dementia who is not affiliated with Pre Diagnostics or the development of its test. He noted that the firm’s approach involving intracellular detection is “very different from other test procedures used to measure proteins and peptides” for Alzheimer’s diagnosis and may provide better performance than other blood-based tests. Nonetheless, the test will require further clinical validation to prove that it can perform better than others, he added.
Read the full article here
February 2021 – Press release
Pre Diagnostics successfully completes proof of concept study for its PreADx immunoassay for detection of Alzheimer’s Disease
Pre Diagnostics announces that its PreADx immunoassay for early detection of Alzheimer’s Disease has successfully completed a clinical evaluation. The company now plans to further optimize the assay in advance of CE marking in Q2, 2021. The company’s focus on innate immunity paves the way for precision medicine approaches to AD.
Akershus University Hospital to Present Poster of Pre Diagnostic’s Immunoassay at AAIC 2020
Akershus University Hospital, Pre Diagnostics scientific partner, presents its poster “A new biological assay measuring Aβ clearance -the Aβ mid-domain immunoassay” at the Alzheimer’s Association International Conference (AAIC) on July 27-31, 2020. The poster discloses details on the development of Pre Diagnostic’s mid-domain Aβ immunoassay and suggests that the test may be useful for measuring disease progression and intervention studies. The AAIC is the world’s largest international conference in the dementia field.
42795_A new biological assay of Aβ clearance
Pre Diagnostics first Research Use Only (RuO) assay
The first version of the data sheet for new Simoa assay for quantitating intracellular Beta Amyloid mid domain peptides in monocytes from peripheral blood is now available
A new blood-based biomarker of Aβ clearance
PreDiagnostics published two posters from its work called “A new blood-based biomarker of Aβ clearance – the monocyte Aβ mid-domain assay” and “Assessing Aβ clearance aided by mass spectrometry” at the Clinical Trials on Alzheimer’s Disease Conference in December 2019.